UNC Division of Plastic & Reconstructive Surgery      UNC Health Care      151 Old University Station Road, Chapel Hill, NC 27514

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Restylane® is the most popular wrinkle filler in North America and in over 70 other countries. Used for over a decade, it treats common wrinkles on the face and has other cosmetic uses as well.

What is Restylane®?

Restylane®, along with similar product Perlane®, contains cross-linked hyaluronic acid, an important structural component of the skin that works to promote hydration and the appearance of suppleness.

Who Can Benefit?

Restylane® is FDA-approved to fill moderate to severe facial wrinkles and folds, but is often also used to fill nasolabial folds, the wrinkles that run from the corners of your nose down to your mouth. Additionally, Restylane® may be used off-label by your plastic surgeon to treat marionette lines, fine lines, hollow tear trough and may also be useful in lip augmentation and facial contouring of the chin, cheeks, and temples.


Before and After Restylane®. Pictures courtesy of Medicis

The Restylane® Procedure

Before beginning the Restylane® treatment, your skin will be thoroughly cleansed with an antiseptic. Your plastic surgeon will carefully select the injection site and inject the Restylane® solution into and below the dermis using a special technique.

Under your skin, the Restylane® combines with your naturally occurring hyaluronic acid and binds to water. A hand massage may be utilized to ensure smoothness and that the Restylane® blends with the adjacent facial contour. Though Restylane® contains lidocaine to manage pain, other pain management treatments may be used.

Restylane® Aftercare

Following your Restylane® treatment, the injection site may feel overly full. Within the first 24 hours, you should avoid strenuous exercise, sun or heat exposure as well as alcohol. These may cause temporary swelling, redness or itching at the injection site. Any swelling can be managed by placing an ice pack over the injection site. Additional possible side effects may include pain or tenderness, lumps or bumps, discoloration or infection. Most side effects are mild or moderate and will last less than a week.

The results of your Restylane® treatment should last 6-12 months, as your body will break down the filler over time. You may also undergo touch-up injections to maintain the correction, but less filler is usually required at that time.

Learn More About Restylane® in Raleigh-Durham

If you are interested in undergoing Restylane® treatments in Chapel Hill to correct wrinkles, we encourage you to call our plastic surgeon Drs. Lynn Damitz at the UNC Aesthetic, Laser & Burn Center to schedule a consultation.

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